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Landmark study revealed for the first time the presence of eprinomectin-resistant intestinal parasites in dairy sheep in France and was selected as “Paper of the Month For Parasitology” by the Cambridge Core Blog

A recent study conducted by a multidisciplinary team has uncovered the presence of eprinomectin-resistant isolates of Haemonchus contortus, a major pathogenic abomasal worm of sheep on five dairy sheep farms from the Pyrénées Atlantiques département in France. This significant research, for which S. Jouffroy (INTHERES, IHAP, CEVA), Damien Achard (CEVA) and Hamadi Karembe (CEVA) were actively involved, has been recognized as the “Paper of the Month for Parasitology” by the Cambridge Core Blog, a new academic content platform hosted by Cambridge University Press.

Using the official World Association for the Advancement of Veterinary Parasitology (WAAVP) guideline test called Fecal Egg Count Reduction Test (FECRT), in parallel with measurement of eprinomectin in serum, the researchers were able to track the presence of resistant H. contortus on the affected farms.

Not only this study did identify eprinomectin-resistant isolates of H. contortus in five flocks but it also confirmed that the use of topical formulation of eprinomectin should be avoided, as it leads to under-dosage and can select for resistant strains in the parasite population.

For the farms not yet facing resistance to eprinomectin, a simple and robust protocol to target and selectively treat lactating ewes with injectable eprinomectin is currently under trial.

The study, which carries great significance for veterinarians, researchers, and sheep farmers, can be accessed freely until July 4th on the Cambridge Core platform.

Learn more: First report of eprinomectin-resistant isolates of Haemonchus contortus in dairy sheep farms in France – Cambridge Core Blog

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