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HEPIZOVAC is the first vaccine in Europe against Epizootic Hemorrhagic Disease (EHD) in cattle.
Epizootic Hemorrhagic Disease (EHD), is a disease affecting ruminants caused by the EHD virus. While the disease is generally asymptomatic in small ruminants, it can be devastating in cattle1. In October 2022, the EHD virus (serotype 8) was first detected in Europe (Sicily and Sardinia) and has since spread rapidly to other European countries1.
Recent outbreaks of EHD in France, Spain, Portugal and Italy caused severe losses for farmers and are threatening neighbouring countries. The disease can impact up to 95% of the animals in a cattle herd2. In the recent EHD-8 outbreaks, the disease has led to symptoms such as fever, loss of appetite, drooling, respiratory distress, ulcers in the mouth, redness of the udder and lameness1,2. Sudden death can occur due to pulmonary edema1. In addition to the impact on the animals, EHD virus causes severe economic losses for producers, impacting the movement of animals within and between countries.
Transmitted by mosquitos, it is a seasonal disease linked to the activity of the vector. After a low incidence in winter and spring, it is anticipated an increased incidence in summer and autumn.
CEVA’s response
Ceva is always working on new ways and products to ease the path for our community of veterinarians and farmers, so to support our customers and authorities in the fight against this devastating disease, Ceva has partnered with CZ Vaccines to make this vaccine available to French veterinarians and farmers.
The vaccine has been licensed for exceptional use in France and will be available starting September 2024.
Juan Munoz Bielsa, Ceva’s Vice-President Marketing Corporate Ruminants, says: “In cooperation with our partner CZ Vaccines, we are happy to make available on the market a very effective vaccine against EHD serotype 8, within a very short period of time. HEPIZOVAC is the first vaccine available in Europe and has been demonstrated to prevent viremia in cattle, which is essential to control the disease. This vaccine is a key tool to protect cattle under our care”.
Reference:
- Jiménez-Cabello, L.; Utrilla-Trigo, S.; Lorenzo, G.; Ortego, J.; Calvo-Pinilla, E. Epizootic Hemorrhagic Disease Virus: Current Knowledge and Emerging Perspectives. Microorganisms 2023, 11, 1339. https://doi.org/10.3390/microorganisms11051339
- Zientara, S., Sailleau, C., Dujardin, P., Bréard, E., & Vitour, D. (2024). Émergence de la maladie hémorragique